nike air mariah Home Improvement Audio Video Artic ? cckxrjtic

[unable to retrieve full-text content]Multi-Zone alternatively Multi-Source function namely,nike air mariah,because the appoint suggests,asics ?, a function surrounded the Receiver is allows it to bring two change audio markers from two vary inputs (i.e. sources) ...

Source: http://zsp29gsd.lateststyle.org/2012/03/08/nike-air-mariah-home-improvement-audio-video-artic/

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JC Whitney Auto Parts & Auto Accessories - Car, Truck, Jeep ...

10% off $75 purchase 15% off $125 purchase use code JCW1015

No thoughts from other users yet ...

Source: http://dealspl.us/Automotive_deals/p_jc-whitney-auto-parts-auto-accessories-car-truck

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Some More Insights on Vision Insurance | unelem.com

[unable to retrieve full-text content]A vision insurance is a kind of insurance policy which is restricted to cover bills incidental to an eye-care check-up, including medical and surgical.

Source: http://www.unelem.com/travel-leisure/travel-tips/some-more-insights-on-vision-insurance

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You Pick: Best Auto Repair Shop in Concord - Concord, MA Patch

Whether your car's in need of a tune-up, a new windshield or a State inspection, there are a handful of places in Concord to go to.?

Our second Best of Patch contest kicks off this week with a focus on the beset auto repair shop in town.?

Here are some of our favorite places, but if we're leaving one off of the list, please let us know in the comments and we'll add it:

Voting in the poll below is open until 9 a.m. Friday. Ties will be broken by whichever business has the most positive comments in the section below. We will announce the winner at noon Friday.

So tell us what your favorite, most reliable place in Concord is to get a tune up, oil change or auto body repairs! And don't forget to tell us in the comments below why you think it's the best place in town.

Because this poll is not scientific, it is not the sole consideration in choosing a winner. A winner will be determined by Patch editors, based on poll results and reviews on?Patch Places. Please vote only once per survey, per Patch.

Source: http://concord.patch.com/articles/you-pick-best-auto-repair-shop-in-concord

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Tot found after twister dies in hospital

By msnbc.com staff

Updated at 5:05 p.m. ET
The?14-month-old girl found in a field after Friday's tornadoes passed away after being taken off life support on Sunday, her grandparents told NBC News.

The grandparents and doctors had earlier decided to remove Angel Babcock from life support due to the severity of her injuries.

Angel was found alive about 150 yards from where her family's home had stood. Her parents, Joe and Moriah Babcock, died instantly; so too did her brother Jaydon, 2 years,?and sister Kendall, 2 months.

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Her grandfather Jack Brough on Saturday?told the Louisville Courier-Journal that?"she?s had a lot of injuries to her head ...?I?m just asking everyone to pray for my granddaughter and for my family."

A neighbor said her boyfriend had tried to help the family leave their mobile home in New Pekin, Ind.,?for his larger one as the tornado bore down on Friday.

The boyfriend, Jason Miller, said he saw Angel's family lying face down in their hallway, holding hands and praying.

As the Friday storm that killed dozens dies down, the scale of the damage is hard to comprehend for those cleaning up debris. NBC's Tom Costello reports.

Before he could help them out, however, the tornado sucked him and the Babcocks out. Miller survived with several broken bones.

Brough said he waited out the storm at his home, and then headed to his daughter's to see how they were.

"As we got closer and closer, the whole area was flattened," he told the Courier-Journal. "I kept saying, ?Oh my God! Oh my God!? I was breathing so hard. I couldn?t see my daughter?s trailer for nothing. It was gone."

Brough was then told of a little boy found in a field and a baby being carried away. He later learned the two were his grandchildren and went to a local hospital to identify them. There he was told that his daughter and her boyfriend were also dead.?

'Total devastation' as cleanup begins
How to help tornado victims

"They wanted me to identify Moriah and Joe, but I just couldn?t do it," he said.?

"She was always happy and loved life,"?Brough said of his daughter. "Her entire life was about Joe and her children. She loved her kids; she was always with them."

Businesses in West Liberty were so damaged by Friday's storm, they will have to come down. NBC's Mike Bettes reports.

NBC News producers Alan Cohen and?Bob Vasilopoulos contributed to this report.

More content from msnbc.com and NBC News

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Source: http://usnews.msnbc.msn.com/_news/2012/03/04/10575527-toddler-found-after-twister-dies-in-hospital

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The Great Style of Old classic Cars ? irc2007.com

Once we say vintage cars, we usually think about the great cars and automobiles which were produced about 30 to 40 years back and maybe even more. Not a lot of them is seen these days, but there is still some considerable quantity of them which many car enthusiasts restore, maintain and treasure.

Being a proud owner of a vintage car though, in not for all. A person may know a lot about cars and the way to fix them, but that is not the main necessity, having money is. The reason being restoring a vintage car may cost a huge sum. One basis for this is that replacement parts can be quite hard to find. If ever, these parts may be expensive or they have to be fabricated and tailor made parts are expensive.

Also, locating a vintage car with its original components that?s still in good working condition may be nearly impossible. Most of these vintage cars have bodies that need extensive body work. It could be extremely hard to find pre fabricated parts of the body for vintage vehicles so car mechanics and the entire body fabricators need to do a lot of work.

Why do people love vintage cars? So why do they shell out huge amounts of money and spend plenty of their time restoring vintage cars? Mostly, the explanation for this is pride. Vintage cars are a fantastic addition to any car collection since these cars represent an era where automobiles in addition to their owners where regarded as the elite as just a number of persons could afford them.

Plus, the vintage cars which can be worthy to be restored are cars which make a significant impact in their era. These cars where the ones that raised the bar in the automobile industry and they should be restored to showcase what they?ve got offered to the industry and why they?ve made such an impact.

Many of these vintage cars are rarely used after they are restored. They are usually driven only every once in awhile and are usually presented in car shows. Owners have a tendency to avoid using them so much while they may be damaged or destroyed. Also, when the vintage car is a model that is highly significant, meaning lots of people have admired them and praised them, they can be much more expensive, especially when restored to their full glory.

While not many restorers have a tendency to part with their vintage car, there are some people who make a business from the jawhorse. Many auctions have recorded huge resale for vintage cars and also this has enticed a lot of people to earn money through it. Many though state that after selling the car, they have an inclination to feel that they have just parted with a significant part of their lives.

For collectors though, having a vintage car is a great supply of pride. Having a piece of automotive history in their garage allows them to feel as if they?re members of an exclusive club. While not all people would love to have a vintage car, for many who do, there is a certain aura of distinction. For these persons, their vintage car is surely an extension of themselves which is what, more than its high fair market price, makes vintage cars truly priceless.

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Source: http://www.irc2007.com/the-great-style-of-old-classic-cars.html

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Pasadena California Bungalow near Rose Bowl and Arroyo Seco

Pasadena is home to many?California Bungalows, noticeably?at the historic landmark called the Bungalow Heaven.? Though, many bungalows are seen here, it?s not the only place you will spot these architectural?homes.? Introducing 1670 Kenneth Way, which is located in North West Pasadena near the Rose Bowl, Arroyo Seco and Brookside Golf Course.

This California Bungalow was built in 1936 and have been remodeled to accommodate features today?s buyers are looking in a home.? It has 3 bedrooms and 2 full bathrooms.? The bedrooms are all spacious, and the master suite offers a walk-in closet.? The living room has a fireplace, and there is a family room which leads to a nice back yard; a perfect place?for entertaining.? The updated kitchen has granite counter tops, custom wood cabinetry, and a charming breakfast bar area.

Outside, both front and back yard landscaping are professionally maintained.? The front porch is an ideal?place to enjoy the colorful blooming flowers.? The views of the San Gabriel Mountains are delightful this time of the year.

Listing courtesy of Micah Lachtman, Coldwell Banker

Features:

List Price:? $588,000

Three bedrooms and Two bathrooms (full)

Built in 1936

1,734 Square Feet interior (public records)

6,441 Square Feet lot size (public records)

2 Car attached garage

Agent Marketing Remark:

Remodeled California Bungalow with updated kitchen, master suite with walk-in closet, huge front porch, hardwood floors and fireplace truly has it all. This beautifully maintained home boasts 3 large bedrooms in an open 1,734 sq.ft. floor plan with separate living and family rooms, as well as a great backyard for entertaining. The kitchen boasts granite counters, custom wood cabinets and breakfast bar. Direct garage access, crown molding, copper plumbing and lush landscaping will spoil you. Just blocks from the Rose Bowl and the Arroyo Seco, it?s proximity to recreation and mountain views will make you want to call this home.

?

If you are interested in this craftsman home, please call or text Ellie Viray at (626) 524-4136 to schedule a private viewing.? You can also find over 500 Pasadena home listings at our new home search site.? Visit and register at Pasadena Home Searcher now.?

Ellie Viray (DRE01239528) is a Realtor-Partner with the Pasadena Views Real Estate Team with over 12 years of experience representing both buyers and sellers.? For a complimentary buyer and seller consultation, call or text Ellie at (626) 524-4136.? Email at Ellie@PasadenaViews.com.

?

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Source: http://www.pasadenaviews.com/pasadena-california-bungalow-ellies-pick-1670-kenneth-way/

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Mayo researchers provide atomic view of a histone chaperone

Public release date: 1-Mar-2012
[ | E-mail | Share ]

Contact: Robert Nellis
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

ROCHESTER, Minn. -- Mayo Clinic researchers have gained insights into the function of a member of a family of specialized proteins called histone chaperones. Using nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography, they have determined the 3-D structure and interactions of the histone chaperone Rtt106 down to the atomic details. The findings are published in the journal Nature.

"The interactions we described are important for gene silencing and the DNA damage response," says senior author Georges Mer, Ph.D., a Mayo Clinic structural biologist. "This is exciting because our newfound knowledge will help us better understand these fundamental cellular processes."

In cells, our DNA is part of a structure called chromatin, comprised of proteins, the majority called histones, which are wrapped with the DNA. Associated with the histones is another group of proteins called histone chaperones, which promote the proper assembly or disassembly of the chromatin during the times our DNA is replicated or repaired when damaged. Their dysfunction has been linked to cancer, aging and other diseases.

The Discovery

Before this Mayo study, scientists knew that the histone chaperone Rtt106 helped in the deposition of histones -- specifically, a complex of histones H3 and H4 -- onto the replicating DNA. They did not understand how Rtt106 does this, given that it does not possess any of the known requirements. Histone H3 is in a modified form where one of its amino acids, lysine 56, is acetylated. Rtt106 does not seem to have an acetylated lysine reader domain.

Mayo researchers discovered two novel domains in Rtt106 that take on this role. One, termed the homodimerization domain, allows two molecules of Rtt106 to be linked so they can cooperate in binding histones H3 and H4. The other, called the double PH domain, is responsible for sensing the acetylated lysine of H3 and further reinforces the interaction. The combined actions of the two domains of Rtt106 enable it to perform the chaperoning function efficiently and properly. This is the first time anyone has described this mode of specific association between a histone chaperone and a modified histone complex.

###

Other authors of the study are Dan Su, M.D., Ph.D.; Qi Hu, Ph.D.; Qing Li, Ph.D.; James Thompson, Ph.D.; Gaofeng Cui, Ph.D.; Ahmed Fazly, Ph.D.; Brian Davies, Ph.D.; Maria Victoria Botuyan, Ph.D.; and Zhiguo Zhang, Ph.D.; all of Mayo Clinic. The study was a collaborative effort between the groups of Dr. Mer and Dr. Zhang and was funded by the National Institutes of Health and Mayo Clinic.

About Mayo Clinic

Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit http://www.mayoclinic.org/about and www.mayoclinic.org/news.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 1-Mar-2012
[ | E-mail | Share ]

Contact: Robert Nellis
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

ROCHESTER, Minn. -- Mayo Clinic researchers have gained insights into the function of a member of a family of specialized proteins called histone chaperones. Using nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography, they have determined the 3-D structure and interactions of the histone chaperone Rtt106 down to the atomic details. The findings are published in the journal Nature.

"The interactions we described are important for gene silencing and the DNA damage response," says senior author Georges Mer, Ph.D., a Mayo Clinic structural biologist. "This is exciting because our newfound knowledge will help us better understand these fundamental cellular processes."

In cells, our DNA is part of a structure called chromatin, comprised of proteins, the majority called histones, which are wrapped with the DNA. Associated with the histones is another group of proteins called histone chaperones, which promote the proper assembly or disassembly of the chromatin during the times our DNA is replicated or repaired when damaged. Their dysfunction has been linked to cancer, aging and other diseases.

The Discovery

Before this Mayo study, scientists knew that the histone chaperone Rtt106 helped in the deposition of histones -- specifically, a complex of histones H3 and H4 -- onto the replicating DNA. They did not understand how Rtt106 does this, given that it does not possess any of the known requirements. Histone H3 is in a modified form where one of its amino acids, lysine 56, is acetylated. Rtt106 does not seem to have an acetylated lysine reader domain.

Mayo researchers discovered two novel domains in Rtt106 that take on this role. One, termed the homodimerization domain, allows two molecules of Rtt106 to be linked so they can cooperate in binding histones H3 and H4. The other, called the double PH domain, is responsible for sensing the acetylated lysine of H3 and further reinforces the interaction. The combined actions of the two domains of Rtt106 enable it to perform the chaperoning function efficiently and properly. This is the first time anyone has described this mode of specific association between a histone chaperone and a modified histone complex.

###

Other authors of the study are Dan Su, M.D., Ph.D.; Qi Hu, Ph.D.; Qing Li, Ph.D.; James Thompson, Ph.D.; Gaofeng Cui, Ph.D.; Ahmed Fazly, Ph.D.; Brian Davies, Ph.D.; Maria Victoria Botuyan, Ph.D.; and Zhiguo Zhang, Ph.D.; all of Mayo Clinic. The study was a collaborative effort between the groups of Dr. Mer and Dr. Zhang and was funded by the National Institutes of Health and Mayo Clinic.

About Mayo Clinic

Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit http://www.mayoclinic.org/about and www.mayoclinic.org/news.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-03/mc-mrp030112.php

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Do You Want Adrenaline? Here Are Some Drifting Games!

What are drifting games? Well. if you love cars and speed you will surely dig these games on account of these are the two things which are in the middle ? a common ground ? and there is no chance which you won?t like taking advantage of each opportunity of feeling alive!

Drifting is type of driving, a genre of car dispute where you will buy at the wheel of a very powerful ride and make sudden moves as which the car looses control. When it looses control you have to perform your boss to have power over it and do some really impressive moves. This sport is actually troubling and deserves a sort in our free sports hall of fame!

The whole thing is which drifting has to be really impressive! When you see the cars turn and when you hear the wheels squeak the moment you are turning the impact power has to be very powerful. that is why this sport is as a rule performed having a large audience around! The impact on the audience is very important and it is something that also decides whether the driver wins or looses. The one who is the greatest familiar is the one who created a certain show and has more chances to finish the race on the first place!The place where you will automobile it will always be on a bumpy terrain, never on the streets or in a city. These games will take you on an adventure across the country!

Here you have to overcome all things the obstacles which come in your method to purchase to the quit. You will also see that still if these games are classical motorcycle games, the internet transformed them into challenging ones, highlighting when is the biggest eminent thing relating to biking ? adventure!

What do you divulge?

Well. I believe that there is a recreational activity that is widely spread and easy for anybody. It?s running! You can run for pleasure, you can take it up as a sport and you may still go-ahead to becoming a professional. Also there is no age limit to practice running. If you pick it to take it as an amusement you don?t have to to concern yourself about the equipment because you just have to take some loose shorts and a t-shirt and you are ready to begin!

acquire ready because a lot of cars are waiting for you to procure in them and make everyone proud of you! You will easily feel how the level of adrenaline is rising and you will become more and more addicted to these games! a few really fun games are waiting for you. get to it!

If you?re a real sports games! amateur and really passionate concerning soccer, then online soccer games are truly a dream come loyal for you, aren?t they?

Source: http://www.short-articles.net/do-you-want-adrenaline-here-are-some-drifting-games/

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